ETF · holdings as filed 2025-09-30
What's inside IBB?
iShares Biotechnology ETF
- Holdings
- 253
- positions in the fund
- Top 10
- 52%
- of fund assets
- Expense ratio
- 0.44%
- net, per year
- Fund size
- $6B
- total net assets
Top 20 holdings
| Rank | Logo | Ticker / Name | Weight | |
|---|---|---|---|---|
| 1 | B  | BISXXBCF INSTITUTIONAL-SL AGNCY | 11.65% | |
| 2 | V  | VRTXVERTEX PHARMACEUTICALS INC | 6.77% | |
| 3 | G  | GILDGILEAD SCIENCES INC | 6.64% | |
| 4 | A  | AMGNAMGEN INC | 6.63% | |
| 5 | R  | REGNREGENERON PHARMACEUTICALS | 5.03% | |
| 6 | A  | ALNYALNYLAM PHARMACEUTICALS INC | 5.02% | |
| 7 | I  | IQVIQVIA HOLDINGS INC | 2.81% | |
| 8 | A  | ARGXARGENX SE - ADR | 2.78% | |
| 9 | I  | INSMINSMED INC | 2.61% | |
| 10 | M  | MTDMETTLER-TOLEDO INTERNATIONAL | 2.20% | |
| 11 | N  | NTRANATERA INC | 1.87% | |
| 12 | O  | ONCBEONE MEDICINES LTD-ADR | 1.86% | |
| 13 | B  | BIIBBIOGEN INC | 1.80% | |
| 14 | U  | UTHRUNITED THERAPEUTICS CORP | 1.61% | |
| 15 | W  | WATWATERS CORP | 1.56% | |
| 16 | I  | INCYINCYTE CORP | 1.43% | |
| 17 | I  | ILMNILLUMINA INC | 1.24% | |
| 18 | G  | GMABGENMAB A/S -SP ADR | 1.22% | |
| 19 | N  | NBIXNEUROCRINE BIOSCIENCES INC | 1.19% | |
| 20 | M  | MEDPMEDPACE HOLDINGS INC | 1.02% |
Top holdings — Health Care
Your 10 largest positions in this sector
1
V
VRTXVERTEX PHARMACEUTICALS INC
6.77%2
G
GILDGILEAD SCIENCES INC
6.64%3
A
AMGNAMGEN INC
6.63%4
R
REGNREGENERON PHARMACEUTICALS
5.03%5
A
ALNYALNYLAM PHARMACEUTICALS INC
5.02%6
A
ARGXARGENX SE - ADR
2.78%7
I
INSMINSMED INC
2.61%8
M
MTDMETTLER-TOLEDO INTERNATIONAL
2.20%9
N
NTRANATERA INC
1.87%10
O
ONCBEONE MEDICINES LTD-ADR
1.86%Top holdings — United States
Your 10 largest positions in this country
1
B
BISXXBCF INSTITUTIONAL-SL AGNCY
11.65%2
V
VRTXVERTEX PHARMACEUTICALS INC
6.77%3
G
GILDGILEAD SCIENCES INC
6.64%4
A
AMGNAMGEN INC
6.63%5
R
REGNREGENERON PHARMACEUTICALS
5.03%6
A
ALNYALNYLAM PHARMACEUTICALS INC
5.02%7
I
IQVIQVIA HOLDINGS INC
2.81%8
I
INSMINSMED INC
2.61%9
M
MTDMETTLER-TOLEDO INTERNATIONAL
2.20%10
N
NTRANATERA INC
1.87%Geography reflects each issuer's registered business address per SEC EDGAR filings where available, falling back to the exchange or listing where no SEC filing exists — not necessarily where a company's stock is primarily listed (e.g. TSMC is classified as Taiwan even though its ADR trades on the NYSE).
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Data source: official SEC Form N-PORT filings (as of 2025-09-30); expense ratio from SEC prospectus (risk/return) filings. Fund holdings are disclosed quarterly and may reflect a 60-day reporting delay.
Informational and educational only — not investment advice.
Informational and educational only — not investment advice.