ETF · holdings as filed 2026-05-31
What's inside SBIO?
ALPS Medical Breakthroughs ETF
- Holdings
- 88
- positions in the fund
- Top 10
- 35%
- of fund assets
- Expense ratio
- 0.50%
- net, per year
- Fund size
- $162M
- total net assets
Top 20 holdings
| Rank | Logo | Ticker / Name | Weight | |
|---|---|---|---|---|
| 1 | A  | ALKSALKERMES PLC | 4.48% | |
| 2 | K  | KYMRKYMERA THERAPEUTICS INC | 4.23% | |
| 3 | C  | CELCCELCUITY INC | 3.92% | |
| 4 | M  | MIRMMIRUM PHARMACEUTICALS INC | 3.90% | |
| 5 | S  | SYRESPYRE THERAPEUTICS INC | 3.68% | |
| 6 | C  | CGONCG ONCOLOGY INC | 3.35% | |
| 7 | A  | APGEAPOGEE THERAPEUTICS INC | 2.93% | |
| 8 | X  | XENEXENON PHARMACEUTICALS INC | 2.90% | |
| 9 | T  | TVTXTRAVERE THERAPEUTICS INC | 2.77% | |
| 10 | D  | DNTHDIANTHUS THERAPEUTICS INC | 2.63% | |
| 11 | N  | NAMSNEWAMSTERDAM PHARMA CO NV | 2.47% | |
| 12 | V  | VKTXVIKING THERAPEUTICS INC | 2.41% | |
| 13 | C  | CRNXCRINETICS PHARMACEUTICALS IN | 2.37% | |
| 14 | A  | ACAACADIA PHARMACEUTICALS INC | 2.35% | |
| 15 | E  | EWTXEDGEWISE THERAPEUTICS INC | 2.33% | |
| 16 | D  | DNLIDENALI THERAPEUTICS INC | 2.12% | |
| 17 | O  | ORKAORUKA THERAPEUTICS INC | 1.80% | |
| 18 | G  | GPCRSTRUCTURE THERAPEUTICS INC | 1.77% | |
| 19 | I  | IRONDISC MEDICINE INC | 1.69% | |
| 20 | I  | IDYAIDEAYA BIOSCIENCES INC | 1.65% |
Top holdings — Health Care
Your 10 largest positions in this sector
1
A
ALKSALKERMES PLC
4.48%2
K
KYMRKYMERA THERAPEUTICS INC
4.23%3
C
CELCCELCUITY INC
3.92%4
M
MIRMMIRUM PHARMACEUTICALS INC
3.90%5
S
SYRESPYRE THERAPEUTICS INC
3.68%6
C
CGONCG ONCOLOGY INC
3.35%7
A
APGEAPOGEE THERAPEUTICS INC
2.93%8
X
XENEXENON PHARMACEUTICALS INC
2.90%9
T
TVTXTRAVERE THERAPEUTICS INC
2.77%10
D
DNTHDIANTHUS THERAPEUTICS INC
2.63%Top holdings — United States
Your 10 largest positions in this country
1
K
KYMRKYMERA THERAPEUTICS INC
4.23%2
C
CELCCELCUITY INC
3.92%3
M
MIRMMIRUM PHARMACEUTICALS INC
3.90%4
S
SYRESPYRE THERAPEUTICS INC
3.68%5
C
CGONCG ONCOLOGY INC
3.35%6
A
APGEAPOGEE THERAPEUTICS INC
2.93%7
T
TVTXTRAVERE THERAPEUTICS INC
2.77%8
D
DNTHDIANTHUS THERAPEUTICS INC
2.63%9
V
VKTXVIKING THERAPEUTICS INC
2.41%10
C
CRNXCRINETICS PHARMACEUTICALS IN
2.37%Geography reflects each issuer's registered business address per SEC EDGAR filings where available, falling back to the exchange or listing where no SEC filing exists — not necessarily where a company's stock is primarily listed (e.g. TSMC is classified as Taiwan even though its ADR trades on the NYSE).
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Data source: official SEC Form N-PORT filings (as of 2026-05-31); expense ratio from SEC prospectus (risk/return) filings. Fund holdings are disclosed quarterly and may reflect a 60-day reporting delay.
Informational and educational only — not investment advice.
Informational and educational only — not investment advice.