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ETF · holdings as filed 2026-03-31

What's inside XBI?

State Street(R) SPDR(R) S&P(R) Biotech ETF
Holdings
155
positions in the fund
Top 10
20%
of fund assets
Expense ratio
—
net, per year
Fund size
$7B
total net assets
Top 15 holdings
1
GVMXXSTATE ST INST US GOV MM-PREM
8.07%
2
APLSUSDAPELLIS PHARMACEUTICALS INC
1.83%
3
ALKSALKERMES PLC
1.45%
4
MDGLMADRIGAL PHARMACEUTICALS INC
1.38%
5
TGTXTG THERAPEUTICS INC
1.35%
6
INSMINSMED INC
1.34%
7
SRRKSCHOLAR ROCK HOLDING CORP
1.30%
8
APGEAPOGEE THERAPEUTICS INC
1.28%
9
PTGXPROTAGONIST THERAPEUTICS INC
1.24%
10
SMMTSUMMIT THERAPEUTICS INC
1.24%
11
UTHRUNITED THERAPEUTICS CORP
1.24%
12
PRAXPRAXIS PRECISION MEDICINES I
1.24%
13
ARWRARROWHEAD PHARMACEUTICALS IN
1.23%
14
COGTCOGENT BIOSCIENCES INC
1.22%
15
BBIOBRIDGEBIO PHARMA INC
1.19%
Sectors
1Health Care
93%
2Unclassified
14%
3Industrials
1%
4Financials
0%
Geography
1United States
102%
2Ireland
2%
3Germany
1%
4Switzerland
1%
5Bermuda
1%
6Virgin Islands, British
0%
7Netherlands
0%
8Unclassified
0%
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Data source: official SEC Form N-PORT filings (as of 2026-03-31); expense ratio from SEC prospectus (risk/return) filings. Fund holdings are disclosed quarterly and may reflect a 60-day reporting delay.
Informational and educational only — not investment advice.